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Brain Health Research

The following research, data, and publications provide the latest knowledge about the benefits of blood pressure control and other modifiable risk factors as a possible mechanism for reducing the risk of future impaired brain health and cognitive decline.


Tracking the landscape of dementia research and resources
Dr. Charlene Liggins, Senior Scientific Program Analyst, Division of Neuroscience, National Institute on Aging. InsideNIA blog; November 28, 2018.

Study Shows Intensive Blood Pressure Control Reduces Risk of Mild Cognitive Impairment (MCI) and the Combined Risk of MCI and Dementia
Alzheimer's Association International Conference 2018; Released July 25, 2018. Jeff D. Williamson.

Summary of the evidence on modifiable risk factors for cognitive decline and dementia: A population-based perspective
Alzheimer’s & Dementia 11 (2015) 718-726. Matthew Baumgart, Heather M. Snyder, Maria C. Carrillo, Sam Fazio, Hye Kim, Harry Johns. http://dx.doi.org/10.1016/j.jalz.2015.05.016

Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke Association
Stroke. 2011;42:2672–2713. Gorelick PB, Scuteri A, Black SE, Decarli C, Greenberg SM, Iadecola C, Launer LJ, Laurent S, Lopez OL, Nyenhuis D, Petersen RC, Schneider JA, Tzourio C, Arnett DK, Bennett DA, Chui HC, Higashida RT, Lindquist R, Nilsson PM, Roman GC, Sellke FW, Seshadri S; American Heart Association Stroke Council, Council on Epidemiology and Prevention, Council on Cardiovascular Nursing, Council on Cardiovascular Radiology and Intervention, and Council on Cardiovascular Surgery and Anesthesia. https://doi.org/10.1161/STR.0b013e3182299496


IADRP: International Alzheimer’s Disease and Related Dementias Research Portfolio with brain illustration

International Alzheimer’s Disease and Related Dementias Research Portfolio
This database catalogs research programs supported by public and private organizations both in the U.S. and abroad, categorized using the Common Alzheimer’s and Related Dementias Research Ontology. The resource is maintained by the NIH National Institute of Aging and NIH Library.

Considerations for the Design of a Systematic Review of Care Interventions for Individuals with Dementia and Their Caregivers: Letter Report
This report provides input into the design of an Agency for Healthcare Research and Quality (AHRQ) systematic review of evidence on effective care-related interventions for people with dementia and their caregivers. It also describes potential changes and considerations for the key questions and study design that would result in the most informative and timely evidence review on this topic. National Academies of Sciences, Engineering, and Medicine. 2018. Washington, DC: The National Academies Press. https://doi.org/10.17226/25326

Preventing Cognitive Decline and Dementia report cover

Preventing Cognitive Decline and Dementia: A Way Forward
This report assesses the current state of knowledge on interventions to prevent cognitive decline and dementia, and informs future research in this area. It also provides recommendations of appropriate content for inclusion in public health messages from the National Institute on Aging. National Academies of Sciences, Engineering, and Medicine (2017). https://doi.org/10.17226/24782

Dementia prevention, intervention, and care
The Lancet Commissions, 390(10113)2673-2734, 2017 Dec 6. Prof Gill Livingston, Andrew Sommerlad, Vasiliki Orgeta, Sergi G Costafreda, Jonathan Huntley, Prof David Ames, Prof Clive Ballard, Prof Sube Banerjee, Prof Alistair Burns, Prof Jiska Cohen-Mansfield, Claudia Cooper, Prof Nick Fox, Laura N Gitlin, Prof Robert Howard, Prof Helen C Kales, Prof Eric B Larson, Prof Karen Ritchie, Prof Kenneth Rockwood, Elizabeth L Sampson, Quincy Samus, Prof Lon S Schneider, Prof Geir Selbæk, Prof Linda Teri, Naaheed Mukadam. https://doi.org/10.1016/S0140-6736(17)31363-6

Cognitive aging report cover

Cognitive Aging: Progress in Understanding and Opportunities for Action
This report assesses the public health dimensions of cognitive aging with an emphasis on definitions and terminology, epidemiology and surveillance, prevention and intervention, education of health professionals, and public awareness and education. It also makes specific recommendations for individuals to reduce the risks of cognitive decline with aging. National Academies of Sciences, Engineering, and Medicine (2015). https://doi.org/10.17226/21693


ACPM and its partners are not responsible for the content or recommendations found in the articles or reports developed by other organizations that have been included in this resource center.

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