Clinical Preventive Services -
Immunizations and Chemoprophylaxis -

Adult Immunizations, Including
Chemoprophylaxis Against Influenza A


ACPM Recommendations:

Adults aged 18 years of age and older without contraindications should receive immunizations for influenza, pneumococcal disease, hepatitis B, tetanus-diphtheria, and measles-mumps-rubella as outlined in the ACIP's Update on Adult Immunization (Table 1). Priorities should include efforts to improve provider and public awareness of the safety and efficacy of adult vaccination; to avoid missed opportunities for vaccination, such as visits to health care providers for other problems, entry into school or employment situations, or travel; to use reminder systems for patients and providers; to have adequate supplies of vaccine; to improve mechanisms for financing and delivery of vaccine; and to assure support for research on better vaccines. Individuals with special risk factors might require additional immunizations.

  • See the entire ACPM recommendation in:

Adult Immunizations. Ann R. Fingar, MD, MPH and Byron J. Francis, MD, FACPM, Illinois Department of Public Health. Am J Prev Med. February 1998.

U.S. Preventive Services Task Force Recommendations:

Annual influenza vaccine is recommended for all persons aged 65 and older and persons in selected high-risk groups (see Clinical Intervention). Pneumococcal vaccine is recommended for all immunocompetent individuals who are age 65 years and older or otherwise at increased risk for pneumococcal disease (see Clinical Intervention). There is insufficient evidence to recommend for or against pneumococcal vaccine for high-risk immunocompromised individuals, but recommendations for vaccinating these persons may be made on other grounds. The series of combined tetanus-diphtheria toxoids (Td) should be completed for adults who have not received the primary series, and all adults should receive periodic Td boosters. Vaccination against measles and mumps should be provided to all adults born after 1956 who lack evidence of immunity. A second measles vaccination is recommended for adolescents and young adults in settings where such individuals congregate (e.g., high schools and colleges). See Screening for Rubella for recommendations for rubella vaccine. Hepatitis B vaccine is recommended for all young adults not previously immunized and for all persons at high risk for infection (see Clinical Intervention). Hepatitis A vaccine is recommended for persons at high risk for hepatitis A virus (HAV) infection (see Clinical Intervention). Varicella vaccine is recommended for susceptible adults (see also Chapter 65). See Screening for Tuberculosis Infection for recommendations regarding the Bacille Calmette-Guérin (BCG) vaccine. Recommendations for postexposure prophylaxis against selected infectious diseases are in Chapter 67; see also Chapter 24, Screening for Hepatitis B Virus Infection.